产品货号：
Z12640
中文名称：
CD18/ITGB2抗体
英文名称：
Anti-CD18/ITGB2 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-CD18/ITGB2 Antibody |
| 指标别名 | CD18;Integrin beta 2;ITGB2;LAD;LCAMB;LFA 1;MAC 1;MF17;MFI7 |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | WB,IHC,IF |
| 基因名称 | ITGB2 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human CD18 recombinant protein (Position:Q404-S769).Human CD18 shares 76% amino acid (aa) sequence identity with mouse CD18. |
| 实际分子量 | 90～100KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | ITGB2(INTEGRIN,BETA-2),also known as CD18,is a protein that in humans is encoded by the ITGB2 gene.ITGB2 is an integrin protein that belongs to the class of cell membrane glycoproteins.The beta-2 integrin chain gene is designated ITGB2 and the leukocyte antigen has been designated CD18.The ITGB2 gene is mapped to 21q22.3.The expression of CD18 is increased in lymphoblastoid cells from persons with Down syndrome,consistent with the location of the gene on chromosome 21.In humans lack of ITGB2 causes Leukocyte Adhesion Deficiency,a disease defined by a lack of leukocyte extravasation from blood into tissues.Although ITGB2 is expressed on the cell surface at normal levels and is capable of function following extracellular stimulation,it could not be activated via the 'inside-out' signaling pathways. |
| Uniprot ID | P05107 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | integrin,beta 2 (complement component 3 receptor 3 and 4 subunit) |
| 蛋白名全称 | Integrin beta-2 |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 Immunofluorescence (IF) 1:50～400 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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